SWI/SNF InfoBase

Citation: Udayakumar Mani, Alagu Sankareswaran S. , Arun Goutham R. N. , Suma Mohan S. (2017) SWI/SNF Infobase—An exclusive information portal for SWI/SNF remodeling complex subunits PLoS ONE 12(9): e0184445

About SWI/SNF Infobase

The SWI/SNF Infobase is an exclusive database of SWI/SNF (SWItch/Sucrose Non-Fermentable) family of remodeling factors. This database comprises subunit information of the BAF(Brahma-associated factor)(Also known as SWI/SNF-α, BAP, SWI/SNF) and PBAF(Polybromo-associated BAF)(Also known as SWI/SNF-β, PBAP, RSC) subfamily of remodeling complexes. These large multi-subunit complexes (~2MDa in size) are formed by the assembly of eight or more subunits, which can be categorized as core, accessory and signature subunits. The information on 27 different SWI/SNF subunits from 20 sequenced organisms, spanning a wide evolutionary range of eukaryotes are available in the database. Totally, a non-redundant set of 522 genes coding for SWI/SNF subunits have been documented in the present version. A detailed annotation on each subunit, including basic protein/gene information, protein sequence, functional domains, gene homologs and missense mutations of human proteins have been provided along with the hyperlink to other relevant public domain databases. This exclusive information portal on SWI/SNF complex subunits would be a valuable resource for the research community working on chromatin remodeling.

Select the Organism Choose BAF PBAF Both

Best viewed in Google Chrome and Mozilla Firefox

Select the Organism Choose BAF PBAF Both

Copyright © 2017. Department of Bioinformatics, SASTRA University