Computational Approaches
Genomewide studies of histone modifications and microRNA expression in disease states
Molecular Simulation and electrostatics of chromatin arrays
Exploring networking patterns among histone variants
Virtual Screening and pharmacophore approaches for epigenetic drug design
Gene Expression Analysis and Pathway mapping
Development of machine learning algorithms for cellular phenotypes
Molecular Dynamics of SIN Mutant nucleosomes (in collaboration with Tom Bishop, Louisiana Tech,USA)

Experimental Interests
Alterations in nuclear architecture during deacetylase inhibition
Epigenetic signatures in cancer progression
Chromatin mediated apoptotic signalling
Lamin perturbations and chromatin signalling
Functional roles of enzyme inhibition on epigenetic states
High Throughput Microscopy based screening